KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1
All Species:
22.42
Human Site:
S174
Identified Species:
37.95
UniProt:
Q13153
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13153
NP_001122092.1
545
60647
S174
T
P
A
V
P
P
V
S
E
D
E
D
D
D
D
Chimpanzee
Pan troglodytes
XP_508657
536
59744
S174
T
P
A
V
P
P
V
S
E
D
E
D
D
D
D
Rhesus Macaque
Macaca mulatta
XP_001090077
545
60664
S174
T
P
A
V
P
P
V
S
E
D
E
D
D
D
D
Dog
Lupus familis
XP_849651
544
60649
V173
E
T
P
A
V
P
P
V
S
E
D
E
D
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O88643
545
60718
S174
T
P
A
V
P
P
V
S
E
D
D
E
D
D
D
Rat
Rattus norvegicus
P35465
544
60559
V173
E
T
P
A
V
P
P
V
S
E
D
E
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509462
527
58159
S174
S
F
Q
L
P
L
I
S
S
S
G
S
L
G
D
Chicken
Gallus gallus
NP_001155844
544
60631
V173
E
T
P
A
V
P
S
V
S
E
D
E
D
D
E
Frog
Xenopus laevis
NP_001079232
564
62749
E192
V
S
E
E
E
D
E
E
E
E
E
E
E
D
D
Zebra Danio
Brachydanio rerio
NP_958485
577
63243
S173
T
P
A
V
A
T
V
S
E
D
E
D
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S272
Y
P
P
M
Y
P
T
S
H
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
F199
Q
G
V
P
P
T
T
F
S
V
N
E
N
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S524
S
P
N
R
S
S
I
S
R
N
A
T
L
K
K
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
Q578
N
Q
T
A
A
Y
Q
Q
Q
L
L
Q
H
Q
Q
Conservation
Percent
Protein Identity:
100
94.3
99.6
96.6
N.A.
97.6
98.9
N.A.
78.7
94.5
80.6
81.9
N.A.
32.7
N.A.
54.7
N.A.
Protein Similarity:
100
95.2
99.6
97
N.A.
98.7
99
N.A.
85.3
96.8
88.3
87.8
N.A.
50.8
N.A.
68.7
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
86.6
26.6
N.A.
20
20
26.6
66.6
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
100
46.6
N.A.
40
46.6
46.6
86.6
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.5
32.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.6
43.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
29
15
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
36
29
29
50
58
58
% D
% Glu:
22
0
8
8
8
0
8
8
43
29
36
43
15
8
15
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
8
0
8
0
0
0
8
8
0
15
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
8
8
0
8
0
0
% N
% Pro:
0
50
29
8
43
58
15
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
8
0
0
0
8
8
8
8
8
15
8
15
15
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
15
8
0
0
8
8
8
58
36
8
0
8
0
0
8
% S
% Thr:
36
22
8
0
0
15
15
0
0
0
0
8
0
0
0
% T
% Val:
8
0
8
36
22
0
36
22
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _